In vivo micro-CT assessment of airway remodeling in a flexible OVA-sensitized murine model of asthma.

Airway remodeling is a major pathological feature of asthma. Up to now, its quantification still requires invasive methods. In this study, we aimed at determining whether in vivo micro-computed tomography (micro-CT) is able to demonstrate allergen-induced airway remodeling in a flexible mouse model...

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Bibliographic Details
Main Authors: Mathieu Lederlin, Annaïg Ozier, Gaël Dournes, Olga Ousova, Pierre-Olivier Girodet, Hugues Begueret, Roger Marthan, Michel Montaudon, François Laurent, Patrick Berger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23119036/pdf/?tool=EBI