Time-dependent effect of severe hypoxia/reoxygenation on oxidative stress level, antioxidant capacity and p53 accumulation in mitochondria of rat heart

The intensity of oxidative stress, protein expression of antiapoptotic Bcl-2 as well as antioxidant enzymes manganese superoxide dismutase (MnSOD) and glutathione peroxidase (GPx) and their regulator p53 were studied in the mitochondria of rat heart. Sessions of repeated hypoxia/reoxygenation ((H/R)...

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Bibliographic Details
Main Authors: O. A. Gonchar, I. N. Mankovska
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2017-12-01
Series:Ukrainian Biochemical Journal
Subjects:
p53
Online Access:http://ukrbiochemjournal.org/2017/12/time-dependent-effect-of-severe-hypoxiareoxygenation-on-oxidative-stress-level-antioxidant-capacity-and-p53-accumulation-in-mitochondria-of-rat-heart.html