Active targeting of orthotopic glioma using biomimetic liposomes co-loaded elemene and cabazitaxel modified by transferritin

Active targeting of orthotopic glioma using biomimetic liposomes co-loaded elemene and cabazitaxel modified by transferritin

Abstract Background Effective treatment of glioma requires a nanocarrier that can cross the blood–brain barrier (BBB) to target the tumor lesion. In the current study, elemene (ELE) and cabazitaxel (CTX) liposomes were prepared by conjugating liposomes with transferrin (Tf) and embedding the cell me...

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Bibliographic Details
Main Authors: Jie Li, Huamin Zeng, Yu You, Rongrong Wang, Tiantian Tan, Weiming Wang, Liyan Yin, Zhaowu Zeng, Yiying Zeng, Tian Xie
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Nanobiotechnology
Subjects:
Glioma
Biomimetic liposomes
Homologous-targeting
Immune escaping
Blood–brain barrier
Transferrin
Online Access:https://doi.org/10.1186/s12951-021-01048-3

Internet

https://doi.org/10.1186/s12951-021-01048-3

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