Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice

Integrin Beta 1 Is Crucial for Urinary Concentrating Ability and Renal Medulla Architecture in Adult Mice

Integrins are heterodimers anchoring cells to the surrounding extracellular matrix (ECM), an active and complex process mediating a series of inside-out and outside-in stimuli regulating cellular turn-over, tissue growth and architecture. Itgb1 is the main subunit of the renal integrins and it is cr...

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Bibliographic Details
Main Authors: Anna Iervolino, Luigi R. De La Motte, Federica Petrillo, Federica Prosperi, Francesca Maria Alvino, Guglielmo Schiano, Alessandra F. Perna, Danilo Di Matteo, Mario De Felice, Giovambattista Capasso, Francesco Trepiccione
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Physiology
Subjects:
integrin beta1
collecting duct
thick ascending limb
renal failure
AQP2
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01273/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01273/full

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