Polarization of migrating monocytic cells is independent of PI 3-kinase activity.

BACKGROUND: Migration of mammalian cells is a complex cell type and environment specific process. Migrating hematopoietic cells assume a rapid amoeboid like movement when exposed to gradients of chemoattractants. The underlying signaling mechanisms remain controversial with respect to localization a...

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Bibliographic Details
Main Authors: Silvia Volpe, Sylvia Thelen, Thomas Pertel, Martin J Lohse, Marcus Thelen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2855346?pdf=render