Divide and conquer: processive transport enables multidrug transporters to tackle challenging drugs

Divide and conquer: processive transport enables multidrug transporters to tackle challenging drugs

Multidrug transporters are membrane proteins that catalyze efflux of antibiotics and other toxic compounds from cells, thereby conferring drug resistance on various organisms. Unlike most solute transporters that transport a single type of compound or similar analogues, multidrug transporters are ex...

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Bibliographic Details
Main Authors: Nir Fluman, Eitan Bibi
Format: Article
Language:English
Published: Shared Science Publishers OG 2014-09-01
Series:Microbial Cell
Subjects:
multidrug resistance
multidrug transport
MdfA
dequalinium
antibiotics
secondary transport
drug-proton exchange
Online Access:http://microbialcell.com/researcharticles/divide-and-conquer-processive-transport-enables-multidrug-transporters-to-tackle-challenging-drugs/

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http://microbialcell.com/researcharticles/divide-and-conquer-processive-transport-enables-multidrug-transporters-to-tackle-challenging-drugs/

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