Causal Effects of Gut Microbiome on Systemic Lupus Erythematosus: A Two-Sample Mendelian Randomization Study

The observational association between gut microbiome and systemic lupus erythematosus (SLE) has been well documented. However, whether the association is causal remains unclear. The present study used publicly available genome-wide association study (GWAS) summary data to perform two-sample Mendelia...

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Bibliographic Details
Main Authors: Kun Xiang, Peng Wang, Zhiwei Xu, Yu-Qian Hu, Yi-Sheng He, Yue Chen, Ya-Ting Feng, Kang-Jia Yin, Ji-Xiang Huang, Jie Wang, Zheng-Dong Wu, Xiao-Ke Yang, De-Guang Wang, Dong-Qing Ye, Hai-Feng Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.667097/full