Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.

Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.

For homeostasis, lingual taste papilla organs require regulation of epithelial cell survival and renewal, with sustained innervation and stromal interactions. To investigate a role for Hedgehog/GLI signaling in adult taste organs we used a panel of conditional mouse models to manipulate GLI activity...

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Bibliographic Details
Main Authors: Alexandre N Ermilov, Archana Kumari, Libo Li, Ariell M Joiner, Marina A Grachtchouk, Benjamin L Allen, Andrzej A Dlugosz, Charlotte M Mistretta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5125561?pdf=render

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http://europepmc.org/articles/PMC5125561?pdf=render

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