Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target

Proteomic analysis of intermediate uveitis suggests myeloid cell recruitment and implicates IL-23 as a therapeutic target

Purpose: To profile vitreous protein expression of intermediate uveitis (IU) patients. Observations: We identified a mean of 363 ± 41 unique proteins (mean ± SD) in IU vitreous and 393 ± 69 unique proteins in control samples using liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis of...

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Bibliographic Details
Main Authors: Yasir J. Sepah, Gabriel Velez, Peter H. Tang, Jing Yang, Teja Chemudupati, Angela S. Li, Quan D. Nguyen, Alexander G. Bassuk, Vinit B. Mahajan
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Proteomics
Vitreous
Biomarker
Intermediate uveitis
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993619300155

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http://www.sciencedirect.com/science/article/pii/S2451993619300155

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