Pathogenic roles of CXCL10 signaling through CXCR3 and TLR4 in macrophages and T cells: relevance for arthritis

Pathogenic roles of CXCL10 signaling through CXCR3 and TLR4 in macrophages and T cells: relevance for arthritis

Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by uncontrolled joint inflammation and destruction of bone and cartilage. We previously reported that C-X-C motif chemokine 10 (CXCL10; also called IP-10) has important roles in joint inflammation and bone de...

Full description

Bibliographic Details
Main Authors: Jong-Ho Lee, Bongjun Kim, Won Jong Jin, Hong-Hee Kim, Hyunil Ha, Zang Hee Lee
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Arthritis Research & Therapy
Subjects:
CXCL10
CXCR3
TLR4
RANKL
Rheumatoid arthritis
Collagen antibody-induced arthritis
Online Access:http://link.springer.com/article/10.1186/s13075-017-1353-6

Internet

http://link.springer.com/article/10.1186/s13075-017-1353-6

Similar Items