Inhibitory Activity of Andrographolide and Andrograpanin on the Rate of PGH2 Formation
Cyclooxygenase (COX) or prostaglandin H2 synthase (PGHS) catalyzes the conversion of arachidonic acid into prostaglandins. Nonsteroidal anti-inflammatory drugs (NSAIDs) work by inhibiting both COX-1 and COX-2 isoforms, thus disturbing this reaction. In Indonesia, Andrographis paniculata (local name:...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Universitas Padjadjaran
2016-12-01
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Series: | Pharmacology and Clinical Pharmacy Research |
Online Access: | http://jurnal.unpad.ac.id/pcpr/article/view/15246/pdf |