Inhibitory Activity of Andrographolide and Andrograpanin on the Rate of PGH2 Formation

Cyclooxygenase (COX) or prostaglandin H2 synthase (PGHS) catalyzes the conversion of arachidonic acid into prostaglandins. Nonsteroidal anti-inflammatory drugs (NSAIDs) work by inhibiting both COX-1 and COX-2 isoforms, thus disturbing this reaction. In Indonesia, Andrographis paniculata (local name:...

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Bibliographic Details
Main Authors: Sri A. Sumiwi, Eli Halimah, Nyi M. Saptarini, Jutti Levita, As'ari Nawawi, Abdul Mutalib, Slamet Ibrahim
Format: Article
Language:English
Published: Universitas Padjadjaran 2016-12-01
Series:Pharmacology and Clinical Pharmacy Research
Online Access:http://jurnal.unpad.ac.id/pcpr/article/view/15246/pdf