An Alphavirus E2 Membrane-Proximal Domain Promotes Envelope Protein Lateral Interactions and Virus Budding

Alphaviruses are members of a group of small enveloped RNA viruses that includes important human pathogens such as Chikungunya virus and the equine encephalitis viruses. The virus membrane is covered by a lattice composed of 80 spikes, each a trimer of heterodimers of the E2 and E1 transmembrane pro...

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Bibliographic Details
Main Authors: Emily A. Byrd, Margaret Kielian, Diane E. Griffin
Format: Article
Language:English
Published: American Society for Microbiology 2017-11-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01564-17