Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

Differential suppression of seizures via Y2 and Y5 neuropeptide Y receptors

Neuropeptide Y (NPY) prominently inhibits epileptic seizures in different animal models. The NPY receptors mediating this effect remain controversial partially due to lack of highly selective agonists and antagonists. To circumvent this problem, we used various NPY receptor knockout mice with the sa...

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Bibliographic Details
Main Authors: David P.D. Woldbye, Avtandil Nanobashvili, Andreas T. Sørensen, Henriette Husum, Tom G. Bolwig, Gunnar Sørensen, Patrik Ernfors, Merab Kokaia
Format: Article
Language:English
Published: Elsevier 2005-12-01
Series:Neurobiology of Disease
Subjects:
NPY
Knockout mice
Zero magnesium
Epilepsy
Brain slice
Kainate
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105001476

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http://www.sciencedirect.com/science/article/pii/S0969996105001476

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