Inhibition of thrombin generation 12 hours after intake of direct oral anticoagulants

Inhibition of thrombin generation 12 hours after intake of direct oral anticoagulants

Abstract Background The residual antithrombotic activity 12 hours after intake of direct oral anticoagulants (DOACs) is of clinical relevance in the setting of bleeding or urgent surgery. Objective To evaluate the effects of DOACs on thrombin generation 12 hours after DOAC intake in comparison to ba...

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Bibliographic Details
Main Authors: Michael Metze, Christian Pfrepper, Tristan Klöter, Stephan Stöbe, Roland Siegemund, Thomas Siegemund, Elvira Edel, Ulrich Laufs, Sirak Petros
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
anticoagulants/therapeutic use
blood coagulation
dabigatran/therapeutic use
factor Xa inhibitors/therapeutic use
thrombin/analysis
thrombin/drug effects
Online Access:https://doi.org/10.1002/rth2.12332

Internet

https://doi.org/10.1002/rth2.12332

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