The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders

The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders

The mitochondrial calcium uniporter (MCU)—a calcium uniporter on the inner membrane of mitochondria—controls the mitochondrial calcium uptake in normal and abnormal situations. Mitochondrial calcium is essential for the production of adenosine triphosphate (ATP); however, excessive calcium will indu...

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Bibliographic Details
Main Authors: Yajin Liao, Yuan Dong, Jinbo Cheng
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:International Journal of Molecular Sciences
Subjects:
MCU
neurodegenerative disorder
inflammation
iron overload
oxidative stress
Online Access:http://www.mdpi.com/1422-0067/18/2/248

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http://www.mdpi.com/1422-0067/18/2/248

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