Dissecting the interaction between HSP70 and vascular contraction: role of $$\hbox{Ca}^{2+}$$ Ca 2 + handling mechanisms

Abstract Heat-shock protein 70 (HSP70) is a ubiquitously expressed molecular chaperone with various biological functions. Recently, we demonstrated that HSP70 is key for adequate vascular reactivity. However, the specific mechanisms targeted by HSP70 to assist in this process remain elusive. Since t...

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Bibliographic Details
Main Authors: Amanda A. de Oliveira, Fernanda Priviero, Rita C. Tostes, R. Clinton Webb, Kenia P. Nunes
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-80966-6