Hydrogen Bond Stability of Quinazoline Derivatives Compounds in Complex against EGFR using Molecular Dynamics Simulation

Lung cancer was a second common cancer case due to the high cigarette smoking activity both in men and women. One of protein receptor which plays an important role in the growth of the tumor is Epidermal Growth Factor Receptor (EGFR). EGFR protein is the most frequent protein mutation in cancer and...

Full description

Bibliographic Details
Main Authors: Herlina Rasyid, Bambang Purwono, Thomas S Hofer, Harno Dwi Pranowo
Format: Article
Language:English
Published: Universitas Gadjah Mada 2019-04-01
Series:Indonesian Journal of Chemistry
Subjects:
Online Access:https://jurnal.ugm.ac.id/ijc/article/view/39567