Brain phenotype of transgenic mice overexpressing cystathionine β-synthase.

Brain phenotype of transgenic mice overexpressing cystathionine β-synthase.

The cystathionine β-synthase (CBS) gene, located on human chromosome 21q22.3, is a good candidate for playing a role in the Down Syndrome (DS) cognitive profile: it is overexpressed in the brain of individuals with DS, and it encodes a key enzyme of sulfur-containing amino acid (SAA) metabolism, a p...

Full description

Bibliographic Details
Main Authors: Vinciane Régnier, Jean-Marie Billard, Sapna Gupta, Brigitte Potier, Stéphanie Woerner, Evelyne Paly, Aurélie Ledru, Sabrina David, Sabrina Luilier, Jean-Charles Bizot, Guido Vacano, Jan P Kraus, David Patterson, Warren D Kruger, Jean M Delabar, Jaqueline London
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3257219?pdf=render

Internet

http://europepmc.org/articles/PMC3257219?pdf=render

Similar Items