Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis

Summary: Brown adipocytes store metabolic energy as triglycerides (TGs) in lipid droplets (LDs). Fatty acids released from brown adipocyte LDs by lipolysis are thought to activate and fuel UCP1-mediated thermogenesis. Here, we test this hypothesis by preventing fatty acid storage in murine brown adi...

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Bibliographic Details
Main Authors: Chandramohan Chitraju, Alexander W. Fischer, Robert V. Farese, Jr., Tobias C. Walther
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720313371