Crystal Structure of the N-Terminal RNA Recognition Motif of mRNA Decay Regulator AUF1
AU-rich element binding/degradation factor 1 (AUF1) plays a role in destabilizing mRNAs by forming complexes with AU-rich elements (ARE) in the 3′-untranslated regions. Multiple AUF1-ARE complexes regulate the translation of encoded products related to the cell cycle, apoptosis, and inflammation. AU...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2016-01-01
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Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2016/3286191 |