Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin.
Dendritic spine development is crucial for the establishment of excitatory synaptic connectivity and functional neural circuits. Alterations in spine morphology and density have been associated with multiple neurological disorders. Autism candidate gene disconnected-interacting protein homolog 2 A (...
Main Authors: | , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-10-01
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Series: | PLoS Biology |
Online Access: | https://doi.org/10.1371/journal.pbio.3000461 |