A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients

A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients

Identifying molecular characteristics that are associated with aggressive cancer phenotypes through gene expression profiling can help predict treatment responses and clinical outcomes. Claudins are deregulated in colorectal cancer (CRC). In CRC, increased claudin-1 expression results in epithelial-...

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Bibliographic Details
Main Authors: Saiprasad Gowrikumar, Mark Primeaux, Kristina Pravoverov, Chao Wu, Bryan C. Szeglin, Charles-Etienne Gabriel Sauvé, Ishwor Thapa, Dhundy Bastola, Xi Steven Chen, J. Joshua Smith, Amar B. Singh, Punita Dhawan
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
claudin-1
claudin-7
CRC
chemoresistance
metastasis
molecular signature
Online Access:https://www.mdpi.com/2073-4409/10/9/2211

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