MASTL induces Colon Cancer progression and Chemoresistance by promoting Wnt/β-catenin signaling

by Srijayaprakash Babu Uppada, Saiprasad Gowrikumar, Rizwan Ahmad, Balawant Kumar, Bryan Szeglin, Xi Chen, J. Joshua Smith, Surinder K. Batra, Amar B. Singh, Punita Dhawan
Published 2018-08-01

A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients

by Saiprasad Gowrikumar, Mark Primeaux, Kristina Pravoverov, Chao Wu, Bryan C. Szeglin, Charles-Etienne Gabriel Sauvé, Ishwor Thapa, Dhundy Bastola, Xi Steven Chen, J. Joshua Smith, Amar B. Singh, Punita Dhawan
Published 2021-08-01

Feasibility and performance of the fecal immunochemical test (FIT) for average-risk colorectal cancer screening in Nigeria.

by Gregory C Knapp, Olusegun Alatise, Bolatito Olopade, Marguerite Samson, Olalekan Olasehinde, Funmilola Wuraola, Oluwole O Odujoko, Akinwunmi O Komolafe, Olujide O Arije, Philip E Castle, J Joshua Smith, Martin R Weiser, T Peter Kingham
Published 2021-01-01

Quantitative assessment of tumor-infiltrating lymphocytes in mismatch repair proficient colon cancer

by Rosa M. Jimenez-Rodriguez, Sujata Patil, Ajaratu Keshinro, Jinru Shia, Efsevia Vakiani, Zsofia Stadler, Neil H. Segal, Rona Yaeger, Tsuyoshi Konishi, Yoshifumi Shimada, Maria Widmar, Iris Wei, Emmanouil Pappou, J. Joshua Smith, Garrett Nash, Philip Paty, Julio Garcia-Aguilar, Martin R. Weiser
Published 2020-01-01

Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters.

by Caitlyn W Barrett, J Joshua Smith, Lauren C Lu, Nicholas Markham, Kristy R Stengel, Sarah P Short, Sarah P Short, Baolin Zhang, Aubrey A Hunt, Barbara M Fingleton, Robert H Carnahan, Michael E Engel, Xi Chen, R Daniel Beauchamp, Keith T Wilson, Scott W Hiebert, Albert B Reynolds, Christopher S Williams
Published 2012-01-01

Genomic stratification beyond Ras/B‐Raf in colorectal liver metastasis patients treated with hepatic arterial infusion

by J. Joshua Smith, Walid K. Chatila, Francisco Sanchez‐Vega, Jashodeep Datta, Louise C. Connell, Bryan C. Szeglin, Azfar Basunia, Taryn M. Boucher, Haley Hauser, Isaac Wasserman, Chao Wu, Andrea Cercek, Jaclyn F. Hechtman, Chris Madden, William R. Jarnagin, Julio Garcia‐Aguilar, Michael I. D'Angelica, Rona Yaeger, Nikolaus Schultz, Nancy E. Kemeny
Published 2019-11-01

KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix

by Jin K. Kim, Michael R. Marco, Seo‐Hyun Choi, Xuan Qu, Chin‐Tung Chen, Moshe Elkabets, Lauren Fairchild, Oliver Chow, Francisco M. Barriga, Lukas E. Dow, Kevin O’Rourke, Bryan Szeglin, Dmitry Yarilin, Sho Fujisawa, Katia Manova‐Todorova, Philip B. Paty, Jinru Shia, Christina Leslie, J. Joshua Smith, Scott Lowe, Raphael Pelossof, Francisco Sanchez‐Vega, Julio Garcia‐Aguilar
Published 2021-10-01

Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated CancerSummary

by Anna L. Means, Tanner J. Freeman, Jing Zhu, Luke G. Woodbury, Paula Marincola-Smith, Chao Wu, Anne R. Meyer, Connie J. Weaver, Chandrasekhar Padmanabhan, Hanbing An, Jinghuan Zi, Bronson C. Wessinger, Rupesh Chaturvedi, Tasia D. Brown, Natasha G. Deane, Robert J. Coffey, Keith T. Wilson, J. Joshua Smith, Charles L. Sawyers, James R. Goldenring, Sergey V. Novitskiy, M. Kay Washington, Chanjuan Shi, R. Daniel Beauchamp
Published 2018-01-01

Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors

by Cristina Valero, Mark Lee, Douglas Hoen, Kate Weiss, Daniel W. Kelly, Prasad S. Adusumilli, Paul K. Paik, George Plitas, Marc Ladanyi, Michael A. Postow, Charlotte E. Ariyan, Alexander N. Shoushtari, Vinod P. Balachandran, A. Ari Hakimi, Aimee M. Crago, Kara C. Long Roche, J. Joshua Smith, Ian Ganly, Richard J. Wong, Snehal G. Patel, Jatin P. Shah, Nancy Y. Lee, Nadeem Riaz, Jingming Wang, Ahmet Zehir, Michael F. Berger, Timothy A. Chan, Venkatraman E. Seshan, Luc G. T. Morris
Published 2021-02-01