Phosphoserine for the generation of lanthanide-binding sites on proteins for paramagnetic nuclear magnetic resonance spectroscopy

<p>Pseudocontact shifts (PCSs) generated by paramagnetic lanthanide ions provide valuable long-range structural information in nuclear magnetic resonance (NMR) spectroscopic analyses of biological macromolecules such as proteins, but labelling proteins site-specifically with a single lanthanid...

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Bibliographic Details
Main Authors: S. Mekkattu Tharayil, M. C. Mahawaththa, C.-T. Loh, I. Adekoya, G. Otting
Format: Article
Language:English
Published: Copernicus Publications 2021-01-01
Series:Magnetic Resonance
Online Access:https://mr.copernicus.org/articles/2/1/2021/mr-2-1-2021.pdf