Disease modeling and stem cell immunoengineering in regenerative medicine using CRISPR/Cas9 systems

CRISPR/Cas systems are popular genome editing tools that belong to a class of programmable nucleases and have enabled tremendous progress in the field of regenerative medicine. We here outline the structural and molecular frameworks of the well-characterized type II CRISPR system and several computa...

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Bibliographic Details
Main Authors: Ainsley Mike Antao, Janardhan Keshav Karapurkar, Dong Ryul Lee, Kye-Seong Kim, Suresh Ramakrishna
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
HLA
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020304931