YAP Translocation Precedes Cytoskeletal Rearrangement in Podocyte Stress Response: A Podometric Investigation of Diabetic Nephropathy

YAP Translocation Precedes Cytoskeletal Rearrangement in Podocyte Stress Response: A Podometric Investigation of Diabetic Nephropathy

Podocyte loss plays a pivotal role in the pathogenesis of glomerular disease. However, the mechanisms underlying podocyte damage and loss remain poorly understood. Although detachment of viable cells has been documented in experimental Diabetic Nephropathy, correlations between reduced podocyte dens...

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Bibliographic Details
Main Authors: Kathryn E. Haley, Mustafa Elshani, In Hwa Um, Cameron Bell, Peter D. Caie, David J. Harrison, Paul A. Reynolds
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
podocytes
diabetic nephropathy
podometrics
YAP
automated image analysis
Hippo signaling
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.625762/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.625762/full

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