Reactive oxygen species mediate TNFR1 increase after TRPV1 activation in mouse DRG neurons

<p>Abstract</p> <p>Background</p> <p>Transient receptor potential vanilloid subtype 1 (TRPV1) is activated by low pH/protons and is well known to be involved in hyperalgesia during inflammation. Tumor necrosis factor α (TNF-α), a proinflammatory cytokine, is involved in...

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Bibliographic Details
Main Authors: Westlund Karin N, Zhang Liping, Ma Fei
Format: Article
Language:English
Published: SAGE Publishing 2009-06-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/31