Resveratrol prevents ammonia toxicity in astroglial cells.

Resveratrol prevents ammonia toxicity in astroglial cells.

Ammonia is implicated as a neurotoxin in brain metabolic disorders associated with hyperammonemia. Acute ammonia toxicity can be mediated by an excitotoxic mechanism, oxidative stress and nitric oxide (NO) production. Astrocytes interact with neurons, providing metabolic support and protecting again...

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Bibliographic Details
Main Authors: Larissa Daniele Bobermin, André Quincozes-Santos, Maria Cristina Guerra, Marina Concli Leite, Diogo Onofre Souza, Carlos-Alberto Gonçalves, Carmem Gottfried
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528750?pdf=render

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http://europepmc.org/articles/PMC3528750?pdf=render

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