Identification of RNPC3 as a novel JAK2 fusion partner gene in B‐acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib

Identification of RNPC3 as a novel JAK2 fusion partner gene in B‐acute lymphoblastic leukemia refractory to combination therapy including ruxolitinib

Abstract Background Hematopoietic neoplasms with chromosomal translocations involving JAK2 are rare, and most of them show myeloproliferative neoplasm‐associated features, followed by B‐acute lymphoblastic leukemia (B‐ALL). De novo B‐ALL cases with JAK2 rearrangements are suggested to be appropriate...

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Bibliographic Details
Main Authors: Xue Chen, Fang Wang, Yang Zhang, Xiaoli Ma, Mingyue Liu, Panxiang Cao, Lin Zhou, Lan Wang, Xian Zhang, Tong Wang, Hongxing Liu
Format: Article
Language:English
Published: Wiley 2020-03-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
B‐acute lymphoblastic leukemia
JAK2
RNPC3
RNPC3‐JAK2
Online Access:https://doi.org/10.1002/mgg3.1110

Internet

https://doi.org/10.1002/mgg3.1110

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