Allosteric communication in myosin V: from small conformational changes to large directed movements.
The rigor to post-rigor transition in myosin, a consequence of ATP binding, plays an essential role in the Lymn-Taylor functional cycle because it results in the dissociation of the actomyosin complex after the powerstroke. On the basis of the X-ray structures of myosin V, we have developed a new no...
Main Authors: | M Cecchini, A Houdusse, M Karplus |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2497441?pdf=render |
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