Allosteric communication in myosin V: from small conformational changes to large directed movements.

The rigor to post-rigor transition in myosin, a consequence of ATP binding, plays an essential role in the Lymn-Taylor functional cycle because it results in the dissociation of the actomyosin complex after the powerstroke. On the basis of the X-ray structures of myosin V, we have developed a new no...

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Bibliographic Details
Main Authors: M Cecchini, A Houdusse, M Karplus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2497441?pdf=render