Cytotoxic activity of Kingella kingae RtxA toxin depends on post-translational acylation of lysine residues and cholesterol binding

Abstract Kingella kingae is a member of the commensal oropharyngeal flora of young children. Improvements in detection methods have led to the recognition of K. kingae as an emerging pathogen that frequently causes osteoarticular infections in children and a severe form of infective endocarditis in...

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Bibliographic Details
Main Authors: Adriana Osickova, Nataliya Balashova, Jiri Masin, Miroslav Sulc, Jana Roderova, Tomas Wald, Angela C. Brown, Evan Koufos, En Hyung Chang, Alexander Giannakakis, Edward T. Lally, Radim Osicka
Format: Article
Language:English
Published: Taylor & Francis Group 2018-11-01
Series:Emerging Microbes and Infections
Online Access:http://link.springer.com/article/10.1038/s41426-018-0179-x