Critical Role of Cysteine-Rich Protein 61 in Mediating the Activation of Renal Fibroblasts

ObjectiveTo explore the expression of cysteine-rich protein 61 (Cyr61) in ischemic renal fibrosis and the role of Cyr61 in mediating the activation of renal fibroblasts.Methods(1) The rat model of renal fibrosis was established after ischemia-reperfusion acute renal injury (IR-AKI). We detected the...

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Bibliographic Details
Main Authors: Hang Liu, Long Zhao, Jisheng Zhang, Chenyu Li, Xuefei Shen, Xuemei Liu, Wei Jiang, Congjuan Luo, Yanfei Wang, Lin Che, Yan Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00464/full