Accounting for Programmed Ribosomal Frameshifting in the Computation of Codon Usage Bias Indices
Experimental evidence shows that synonymous mutations can have important consequences on genetic fitness. Many organisms display codon usage bias (CUB), where synonymous codons that are translated into the same amino acid appear with distinct frequency. Within genomes, CUB is thought to arise from s...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Oxford University Press
2018-10-01
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Series: | G3: Genes, Genomes, Genetics |
Subjects: | |
Online Access: | http://g3journal.org/lookup/doi/10.1534/g3.118.200185 |