Human Chitotriosidase: Catalytic Domain or Carbohydrate Binding Module, Who’s Leading HCHT’s Biological Function

Abstract Chitin is an important structural component of numerous fungal pathogens and parasitic nematodes. The human macrophage chitotriosidase (HCHT) is a chitinase that hydrolyses glycosidic bonds between the N-acetyl-D-glucosamine units of this biopolymer. HCHT belongs to the Glycoside Hydrolase...

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Bibliographic Details
Main Authors: Oscar Crasson, Gaston Courtade, Raphaël R. Léonard, Finn Lillelund Aachmann, François Legrand, Raffaella Parente, Denis Baurain, Moreno Galleni, Morten Sørlie, Marylène Vandevenne
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02382-z