Cholesterol-Ester Transfer Protein Alters M1 and M2 Macrophage Polarization and Worsens Experimental Elastase-Induced Pulmonary Emphysema

Cholesterol-Ester Transfer Protein Alters M1 and M2 Macrophage Polarization and Worsens Experimental Elastase-Induced Pulmonary Emphysema

Cholesterol-ester transfer protein (CETP) plays a role in atherosclerosis, the inflammatory response to endotoxemia and in experimental and human sepsis. Functional alterations in lipoprotein (LP) metabolism and immune cell populations, including macrophages, occur during sepsis and may be related t...

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Bibliographic Details
Main Authors: Kelly Gomes Santana, Renato Fraga Righetti, Cristiane Naffah de Souza Breda, Omar Alberto Domínguez-Amorocho, Theresa Ramalho, Francisca Elda B. Dantas, Valéria Sutti Nunes, Iolanda de Fátima Lopes Calvo Tibério, Francisco Garcia Soriano, Niels O. S. Câmara, Eder Carlos Rocha Quintão, Patrícia M. Cazita
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
cholesterol ester transfer protein
macrophage—cell
inflammation
chronic obstructive pulmonary disease
pulmonary emphysema
interleukin-10
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.684076/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.684076/full

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