Regulatory Mechanisms of the NLRP3 Inflammasome, a Novel Immune-Inflammatory Marker in Cardiovascular Diseases

Regulatory Mechanisms of the NLRP3 Inflammasome, a Novel Immune-Inflammatory Marker in Cardiovascular Diseases

The nod-like receptor family pyrin domain containing 3 (NLRP3) is currently the most widely studied inflammasome and has become a hot topic of recent research. As a macromolecular complex, the NLRP3 inflammasome is activated to produce downstream factors, including caspase-1, IL-1β, and IL-18, which...

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Bibliographic Details
Main Authors: Na An, Yonghong Gao, Zeyu Si, Hanlai Zhang, Liqin Wang, Chao Tian, Mengchen Yuan, Xinyu Yang, Xinye Li, Hongcai Shang, Xingjiang Xiong, Yanwei Xing
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
NLRP3 inflammasome
cardiovascular diseases
immune-inflammatory
coronary atherosclerosis
myocardial ischemia/reperfusion
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01592/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.01592/full

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