Oncogenic role of dysregulated leptin signaling in the pathogenesis of ovarian cancer

Abstract Leptin, a pleiotropic hormone is produced by adipose tissues and plays a critical role in various biological functions. Leptin mediates its function through interaction with specific receptors. The leptin-receptor interaction modulates activation of a number of signaling pathways, such as J...

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Bibliographic Details
Main Authors: Iman W. Achkar, Ajaz A. Bhat, Maria Zafar, Madiha Abbas, Omar S. Khan, Shilpa Kuttikrishnan, Kirti S. Prabhu, Shahab Uddin
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Translational Medicine Communications
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41231-018-0031-2