Amyloid precursor protein is trafficked and secreted via synaptic vesicles.

Amyloid precursor protein is trafficked and secreted via synaptic vesicles.

A large body of evidence has implicated amyloid precursor protein (APP) and its proteolytic derivatives as key players in the physiological context of neuronal synaptogenesis and synapse maintenance, as well as in the pathology of Alzheimer's Disease (AD). Although APP processing and release ar...

Full description

Bibliographic Details
Main Authors: Teja W Groemer, Cora S Thiel, Matthew Holt, Dietmar Riedel, Yunfeng Hua, Jana Hüve, Benjamin G Wilhelm, Jürgen Klingauf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21556148/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21556148/?tool=EBI

Similar Items