Quantification of Plasmodium knowlesi versus Plasmodium falciparum in the rhesus liver: implications for malaria vaccine studies in rhesus models

Abstract Background Rhesus macaques are valuable pre-clinical models for malaria vaccine development. The Plasmodium knowlesi/rhesus and Plasmodium falciparum/rhesus models are two established platforms for malaria vaccine testing, and both have previously been used to assess live-attenuated sporozo...

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Bibliographic Details
Main Authors: Melanie J. Shears, Annette M. Seilie, B. Kim Lee Sim, Stephen L. Hoffman, Sean C. Murphy
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Malaria Journal
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12936-020-03385-4