Biochemical characterization of the placeholder nucleosome for DNA hypomethylation maintenance

DNA methylation functions as a prominent epigenetic mark, and its patterns are transmitted to the genomes of offspring. The nucleosome containing the histone H2A.Z variant and histone H3K4 mono-methylation acts as a “placeholder” nucleosome for DNA hypomethylation maintenance in zebrafish embryonic...

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Bibliographic Details
Main Authors: Rina Hirano, Tomoya Kujirai, Lumi Negishi, Hitoshi Kurumizaka
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580819300317