The impact of early phase price agreements on prices of orphan drugs

Abstract Background Innovative orphan drugs often have an incremental cost-effectiveness ratio (ICER) which is higher than the maximum threshold for reimbursement. Payers have limited budgets and often cannot pay the full price of a new product, but pharmaceutical and biotechnology companies require...

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Bibliographic Details
Main Authors: Mark Nuijten, Philippe Van Wilder
Format: Article
Language:English
Published: BMC 2021-03-01
Series:BMC Health Services Research
Subjects:
Online Access:https://doi.org/10.1186/s12913-021-06208-7