Silylated Tag-Assisted Peptide Synthesis: Continuous One-Pot Elongation for the Production of Difficult Peptides under Environmentally Friendly Conditions

Silylated Tag-Assisted Peptide Synthesis: Continuous One-Pot Elongation for the Production of Difficult Peptides under Environmentally Friendly Conditions

Addition of the silylated tag (STag) enables peptides to be highly soluble in CPME, allowing them to be used at high concentrations in a coupling reaction to enhance reactivity and achieve effective synthesis of sterically hindered peptides. We described the development of a continuous one-pot STag-...

Full description

Bibliographic Details
Main Authors: Shinya Yano, Toshihiro Mori, Hideki Kubota
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Molecules
Subjects:
peptide synthesis
chemical tag
one-pot
green chemistry
Online Access:https://www.mdpi.com/1420-3049/26/12/3497

Internet

https://www.mdpi.com/1420-3049/26/12/3497

Similar Items