A novel statistic for genome-wide interaction analysis.

Although great progress in genome-wide association studies (GWAS) has been made, the significant SNP associations identified by GWAS account for only a few percent of the genetic variance, leading many to question where and how we can find the missing heritability. There is increasing interest in ge...

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Bibliographic Details
Main Authors: Xuesen Wu, Hua Dong, Li Luo, Yun Zhu, Gang Peng, John D Reveille, Momiao Xiong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2944798?pdf=render