Prognostic significance of pre-treatment ALBI grade in advanced non-small cell lung cancer receiving immune checkpoint therapy

Abstract The liver is an essential organ for regulating innate and acquired immunity. We hypothesized that the pre-treatment hepatic function affects the clinical outcome of immune checkpoint inhibitors (ICIs) in non-small cell lung cancer (NSCLC). We analyzed 140 patients with NSCLC who received IC...

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Bibliographic Details
Main Authors: Ryosuke Matsukane, Hiroyuki Watanabe, Kojiro Hata, Kimitaka Suetsugu, Toshikazu Tsuji, Nobuaki Egashira, Yoichi Nakanishi, Isamu Okamoto, Ichiro Ieiri
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94336-9