Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats.

Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and immunocompromised individuals. The lack of a safe and effective RSV vaccine represents a major unmet medical need. RSV fusion (F) surface glyco...

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Bibliographic Details
Main Authors: Gale Smith, Rama Raghunandan, Yingyun Wu, Ye Liu, Michael Massare, Margret Nathan, Bin Zhou, Hanxin Lu, Sarathi Boddapati, Jingning Li, David Flyer, Gregory Glenn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511306?pdf=render