Auto3DCryoMap: an automated particle alignment approach for 3D cryo-EM density map reconstruction
Abstract Background Cryo-EM data generated by electron tomography (ET) contains images for individual protein particles in different orientations and tilted angles. Individual cryo-EM particles can be aligned to reconstruct a 3D density map of a protein structure. However, low contrast and high nois...
Main Authors: | Adil Al-Azzawi, Anes Ouadou, Ye Duan, Jianlin Cheng |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-12-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-020-03885-9 |
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