Auto3DCryoMap: an automated particle alignment approach for 3D cryo-EM density map reconstruction

Auto3DCryoMap: an automated particle alignment approach for 3D cryo-EM density map reconstruction

Abstract Background Cryo-EM data generated by electron tomography (ET) contains images for individual protein particles in different orientations and tilted angles. Individual cryo-EM particles can be aligned to reconstruct a 3D density map of a protein structure. However, low contrast and high nois...

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Bibliographic Details
Main Authors: Adil Al-Azzawi, Anes Ouadou, Ye Duan, Jianlin Cheng
Format: Article
Language:English
Published: BMC 2020-12-01
Series:BMC Bioinformatics
Subjects:
Cryo-EM
3D density map
Particle alignment
Particle picking
Protein structure
Online Access:https://doi.org/10.1186/s12859-020-03885-9

Internet

https://doi.org/10.1186/s12859-020-03885-9

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