Acetoacetate reduces growth and ATP concentration in cancer cell lines which over-express uncoupling protein 2

<p>Abstract</p> <p>Background</p> <p>Recent evidence suggests that several human cancers are capable of uncoupling of mitochondrial ATP generation in the presence of intact tricarboxylic acid (TCA) enzymes. The goal of the current study was to test the hypothesis that k...

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Bibliographic Details
Main Authors: Quadros Edward V, Miller Anna, Fine Eugene J, Sequeira Jeffrey M, Feinman Richard D
Format: Article
Language:English
Published: BMC 2009-05-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/9/1/14