HPLC method development and validation for the estimation of axitinibe in rabbit plasma

ABSTRACT A rapid, sensitive, and accurate high performance liquid chromatography for the determination of axitinibe (AN) in rabbit plasma is developed using crizotinibe as an internal standard (IS). Axitinibe is a tyrosine kinase inhibitor, used in the treatment of advanced kidney cancer, which work...

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Bibliographic Details
Main Authors: Achanta Suneetha, Sharmila Donepudi
Format: Article
Language:English
Published: Universidade de São Paulo 2017-10-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300607&lng=en&tlng=en